Microcirculation is the delivery of fresh blood to
the smallest blood vessels, present in the vasculature embedded within organ
tissues.Arterioles carry the blood to the capillaries. Blood flows out of the
capillaries into the venules. Arterioles contract and relax, varying their
diameter and vascular tone, as the vascular smooth muscle responds to diverse
stimuli.The term capillary exchange refers to all exchanges at microcirculatory
level, most of which occurs in the capillaries. Sites where material exchange
occurs between the blood and tissues are the capillaries. Capillary walls allow
the free flow of almost every substance in plasma except plasma
protein.Diffusion is the first and most important mechanism that allows the
flow of small molecules across capillaries. The process depends on the
difference of gradients between the interstitium and blood. The Starling equation is an
equation that describes the roles of hydrostatic and osmotic forces (the so-called Starling forces)
in the movement of fluid acrosscapillary endothelium.
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